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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALK
All Species:
16.67
Human Site:
S319
Identified Species:
36.67
UniProt:
Q9UM73
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UM73
NP_004295.2
1620
176428
S319
S
K
E
M
P
R
G
S
F
L
L
L
N
T
S
Chimpanzee
Pan troglodytes
XP_001149706
864
91681
Rhesus Macaque
Macaca mulatta
XP_001093184
1289
140035
A87
L
K
A
G
R
P
E
A
R
G
S
L
A
L
D
Dog
Lupus familis
XP_540136
1905
205583
S609
S
K
E
M
P
R
G
S
F
L
L
L
N
T
S
Cat
Felis silvestris
Mouse
Mus musculus
P97793
1621
174901
S323
S
Q
E
M
P
R
G
S
F
L
L
L
N
T
S
Rat
Rattus norvegicus
XP_001067235
1617
174797
S323
L
K
E
M
P
R
G
S
F
L
L
L
N
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419364
1584
172486
S285
S
E
N
T
P
K
G
S
F
L
F
L
N
A
S
Frog
Xenopus laevis
Q9PVZ4
1362
153727
K158
R
G
S
V
R
I
E
K
N
N
E
L
C
Y
L
Zebra Danio
Brachydanio rerio
XP_691964
1386
150370
G184
C
G
W
Q
P
V
Q
G
R
G
P
Q
W
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_652600
1701
185560
F337
I
D
D
A
N
G
H
F
L
Y
A
R
V
N
P
Honey Bee
Apis mellifera
XP_392254
1436
158335
H234
R
P
L
N
W
T
L
H
R
G
A
T
P
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.2
75.8
78.3
N.A.
87.1
88
N.A.
N.A.
69.8
20
42.1
N.A.
28.2
31.3
N.A.
N.A.
Protein Similarity:
100
39.5
77
81
N.A.
90.4
90.8
N.A.
N.A.
81.1
35.1
54.9
N.A.
42.7
46.5
N.A.
N.A.
P-Site Identity:
100
0
13.3
100
N.A.
93.3
93.3
N.A.
N.A.
60
6.6
6.6
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
0
20
100
N.A.
100
93.3
N.A.
N.A.
73.3
13.3
13.3
N.A.
6.6
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
0
10
0
0
19
0
10
10
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
10
37
0
0
0
19
0
0
0
10
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
10
46
0
10
0
0
0
0
% F
% Gly:
0
19
0
10
0
10
46
10
0
28
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
37
0
0
0
10
0
10
0
0
0
0
0
0
0
% K
% Leu:
19
0
10
0
0
0
10
0
10
46
37
64
0
10
10
% L
% Met:
0
0
0
37
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
10
0
0
0
10
10
0
0
46
10
0
% N
% Pro:
0
10
0
0
55
10
0
0
0
0
10
0
10
0
10
% P
% Gln:
0
10
0
10
0
0
10
0
0
0
0
10
0
0
0
% Q
% Arg:
19
0
0
0
19
37
0
0
28
0
0
10
0
10
0
% R
% Ser:
37
0
10
0
0
0
0
46
0
0
10
0
0
10
46
% S
% Thr:
0
0
0
10
0
10
0
0
0
0
0
10
0
37
0
% T
% Val:
0
0
0
10
0
10
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
10
0
10
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _